This study optimized amodiaquine analogs to combat drug-resistant Plasmodium falciparum. Structural modifications yielded compound 43 (ADC-028), which showed nanomolar ac [...]

Conventional dendritic cell (cDC) cross-presentation of tumor antigen within the lymph nodes is critical for antitumor immunity via the priming of tumor-specific CD8+ T c [...]

This dissertation contributes a validated, generalizable imaging platform, new mechanistic insight into contact-driven signaling in metastasis and therapy resistance, and [...]

Abstraction of mental health data from the electronic health record was combined with transplant registry and pre-transplant psychological interview data to explore the r [...]

This project investigates the informatics architecture required to realize a continuous Learning Health System (LHS) in intensive care using offline reinforcement learnin [...]

This quality improvement paper describes the development and implementation of a standardized gastric point-of-care ultrasound (POCUS) workflow to improve aspiration-risk [...]

Malaria infection during pregnancy remains a major public health concern in the WHO African Region, with an estimated 13 million pregnancies affected by malaria across 33 [...]

The experiments contained within this dissertation explore the behavioral, endocrine, and molecular factors involved in the relationship between thyroid hormone signaling [...]

Ruth Tadesse discusses her path from childhood in Ethiopia and immigration to the United States to a career in nursing, nursing education, and gerontological research. Sh [...]

This dissertation examined the pharmaco-epidemiology of non-CF bronchiectasis and the use of inhaled antibiotics in routine US care using longitudinal administrative clai [...]