|
1.
|
Immune checkpoint blockade (ICB) therapy targets checkpoint proteins to restore normal function to the immune system so that it can attack cancer cells. It is used succes [...]
2024 |
Abstract |
|
|
2.
|
|
|
3.
|
Next generation sequencing (NGS) and single-cell sequencing technologies have enabled unparalleled resolution of the cell's molecular machinery; however, gleaning accurat [...]
2021 |
Abstract |
|
|
4.
|
Schizophrenia (SCZ) is a complex neuropsychiatric disorder thought to arise from an interplay of environmental and genetic risk factors. The presentation of disease sympt [...]
2023-12-05 |
Dissertation |
|
|
5.
|
This dissertation describes the implementation of a technique for using cellular miRNAs as tools for the discovery of virus-host interactions. With this methodology, I di [...]
2017 |
Dissertation |
|
|
6.
|
Cancers are among the most deadly and intractable of human diseases, for which the standard of care may involve aggressive yet only partially effective therapies. Immunot [...]
2022 |
Dissertation |
|
|
7.
|
|
|
8.
|
Extracellular vesicles (EVs) transfer critical information for intercellular communication and function by releasing cargo microRNA (miRNA) into target acceptor cells. Up [...]
2021 |
Abstract |
|
|
9.
|
This thesis work highlights development and applications for both circulating extracellular vesicles (EV) and cell-free RNA (cf-RNA) toward liquid biopsy based early canc [...]
2021 |
Dissertation |
|
|
10.
|
The overwhelming majority (~90%) of patients with pancreatic ductal adenocarcinoma (PDAC) will be treated with systemic standard-of-care chemotherapeutic regimens at some [...]
2022 |
Dissertation |
|
