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Central nervous system demyelination occurs in numerous conditions, including multiple sclerosis (MS). Remyelination in acute lesions involves the recruitment and maturat [...]

Myelin ensheaths axons and increases their conduction velocities. In the central nervous system (CNS) myelin is produced by oligodendrocytes (OLs) that differentiate from [...]

Myelination in the CNS is essential for neuronal function, and oligodendrocytes achieve this by wrapping axons with multilayered myelin sheaths. We identify FBXW7 as a ke [...]