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The goal of this dissertation is to improve our understanding of the factors governing genetic repair to facilitate whole gene insertion into the genome of mature organis [...]
2025-02-07 | Dissertation |
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Head and neck squamous cell carcinoma (HNSCC) is known to have a high progression rate in certain subpopulations, despite existing treatment methods. Due to the lack of s [...]
2016-09-01 | Thesis |
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Scientific and technological developments have made it possible to test human DNA for the presence of abnormalities associated with some inherited disorders. This genetic [...]
2009 | Capstone |
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With the advent of next-generation sequencing techniques like RNA-Seq, there is the potential for unbiased transcriptome-wide analysis of gene expression and alternative [...]
2009 | Thesis |
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Single nucleotide polymorphism genotyping provides a method of genotyping ideally suited to high throughput operations. However, individual variation at SNP loci presents [...]
2005 | Thesis |
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Genomic screening is an increasingly important part of cancer care. Screening often detects somatic variants in the tumor sample of varied clinical significance: some are [...]
2019 | Capstone |