I have developed a co-mutation frequency network to infer functional redundancy between pairs of cancer genes. This analysis builds on previous work that leverages mutual [...]

Zoonoses— infectious diseases transmitted between animals and humans—inflict a heavy toll on the economy, health, and livelihood worldwide. One Health serves as a framewo [...]

Schizophrenia (SCZ) is a complex neuropsychiatric disorder thought to arise from an interplay of environmental and genetic risk factors. The presentation of disease sympt [...]

Designing synthetic genes for heterologous expression is a keystone of synthetic biology. In protein sequences - as there are 61 sense codons but only 20 standard amino a [...]

Globally, attention-deficit/hyperactivity disorder (ADHD), affects children, adolescents and adults, and can cause reduced academic achievement, occupational struggles, a [...]

The significant inter- and intra-tumor heterogeneity observed in breast cancer patients presents an ongoing challenge that impedes accurate disease characterization and c [...]

Patient stratification is essential for addressing breast cancer's inter- and intra-heterogeneity. While the PAM50 classifier is widely regarded to be the gold standard f [...]

Biochemical reaction networks, mathematical models that describe the dynamic interrelationships between biochemical species, facilitate studying complex biological proces [...]