Axons can represent the majority of a neuron's volume and are energetically demanding. Specialized glia ensheathe axons to insulate them and are believed to support axon [...]

Neuropathy Target Esterase (NTE) is an enzyme localized to the ER that regulates Protein Kinase A (PKA) signaling and maintains lipid homeostasis. Exposure to a neurotox [...]

Glial cells refine synaptic signaling, ensheath axonal projections and, importantly, are the first immune responders in the brain after trauma or stress. During reactiv [...]

Recent advances in glial cell research have proven that glial cells are much more than brain “glue,” and that glia perform numerous important functions in vertebrate and [...]

Current treatments for FTD mitigate some behavioral changes, but there are no therapies that prevent or slow the progression of the disease. Profiling the epigenetic chan [...]

Amyotrophic Lateral Sclerosis is the most common adult onset motor neurodegenerative disease. The etiology of the disease remains obscure, and as such there is no effecti [...]