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This dissertation explores the capacity of direct chemical modification of existing aptamer structures for the discovery of novel functional applications using a closely [...]
2021 |
Dissertation |
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Next generation sequencing (NGS) and single-cell sequencing technologies have enabled unparalleled resolution of the cell's molecular machinery; however, gleaning accurat [...]
2021 |
Abstract |
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Successful cancer treatment continues to elude modern medicine and its arsenal of therapeutic strategies. Therapy resistance is driven by tumor heterogeneity, complex int [...]
2021 |
Dissertation |
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