1.
Identification of druggable mutations in Acute Myeloid Leukemia (AML), such as FLT3-ITD, has led to the development of targeted therapies capable of out-performing cytoto [...]
2022 | Abstract |
2.
This thesis describes fibroblast growth factor signaling in the development of resistance to tyrosine kinase inhibitor therapy in solid and hematologic malignancies, and [...]
2016-08-01 | Dissertation |
3.
Acute Myeloid Leukemia (AML) is an aggressive cancer with poor overall survival due to frequent relapse. FMS-like tyrosine kinase (FLT3) is the most commonly mutated gene [...]
2022 | Abstract |
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Gene transcription is fundamental in establishing and maintaining cell identity and function. All normal cells are encoded with the same DNA, so transcription is essentia [...]
2024-02-23 | Dissertation |
7.
Contributing to proteomic diversity, alternative splicing of pre-mRNA is widespread in the human transcriptome and can greatly influence regulation of both normal and dis [...]
2020 | Dissertation |
8.
November 2013 issue of the Scribe. Contents include clinical trials for acute myeloid leukemia treatment, care for senior patients, liability insurance, management of use [...]
2013-11 | Other | Medical Society of Metropolitan Portland records |
9.
Despite decades of conventional chemotherapy, the prognosis for patients with acute myeloid leukemia (AML) remains dismal, with 75% of patients succumbing to their diseas [...]
2021 | Non-thesis manuscript |
10.
This thesis is composed of two studies that utilizes different statistical methods to answer cancer research questions. The first study uses supervised and unsupervised s [...]
2023-09-13 | Dissertation |