Public omics datasets from sequencing and array-based platforms now amount to millions of samples across thousands of studies and projects. This wealth of data is difficu [...]

The goal of this project is to document the bioinformatics tasks currently carried out by researchers in the fields of genomics and proteomics. This will help us identify [...]

Alzheimer s Disease (AD) is the leading cause of dementia in the United States yet the genetics behind this complex disease remains unclear. With the exception of Apolipo [...]

Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignancy with a marked propensity for liver metastasis and a poor overall prognosis. Although canonical d [...]

Formaldehyde, a widely used industrial chemical and environmental pollutant, is classified as a human carcinogen due to its association with nasopharyngeal cancer and mye [...]

The gut microbiome is involved in promoting or inhibiting (protecting against or contributing to the development of) many diseases, such as diabetes, inflammatory bowel d [...]

Genome-wide studies depend heavily on the quality and consistency of integrated annotation data from diverse computational and experimental sources. This thesis presents [...]

Genomic structural variations are an important class of genetic variants with a wide va- riety of functional impacts. The detection of structural variations using high-th [...]

Enterohemorrhagic (EHEC) and enteropathogenic (EPEC) Escherichia coli strains pose significant health risks but are difficult to detect in environmental samples due to lo [...]