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Public omics datasets from sequencing and array-based platforms now amount to millions of samples across thousands of studies and projects. This wealth of data is difficu [...]

Due to the complexity of BCR/ABL-independent TKI resistance, a central question is whether relapse acts through the canonical BCR/ABL CML pathways seen in dependent cases [...]

Cancer is now the biggest single cause of mortality worldwide, incidence has increased by 11% in four years and cases are forecast to rise by 75% over the next 20 years [ [...]

The research to be presented in this thesis addresses the topic of information gathering, information extraction and information filtering in the area of bioinformatics. [...]

Acute cardiac injury with renal injury (acute cardiorenal syndrome) can induce chronic kidney disease (CKD), but mechanisms by which heart injury signals to kidney are un [...]

Black and white photograph of Christopher Mathews, Ph.D., Professor and Chairman of Oregon State Universitys Department of Biochemistry and Biophysics, and Peter von Hipp [...]

In the study of rare and undiagnosed diseases it is of critical importance to identify potential gene candidates for those disease in order to establish an appropriate t [...]

Enormous data collection efforts and improvements in technology have made large-scale genome-wide association studies (GWAS) a promising approach to better understanding [...]