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Designing synthetic genes for heterologous expression is a keystone of synthetic biology. In protein sequences - as there are 61 sense codons but only 20 standard amino a [...]

HER2-positive breast cancer is an aggressive subtype of breast cancer with patients having significantly lower survival rates compared to other breast cancers. HER2-posit [...]

Identification of biologically relevant high-occupancy transcription factor binding sites (TFBS) in silico has historically been a difficult problem with a high error rat [...]

The significant inter- and intra-tumor heterogeneity observed in breast cancer patients presents an ongoing challenge that impedes accurate disease characterization and c [...]

Gene expression profiles and mass-spectrometry analysis of a plaque have revealed genes and proteins involved in atherosclerotic plaque progression. Though differentially [...]

Biochemical reaction networks, mathematical models that describe the dynamic interrelationships between biochemical species, facilitate studying complex biological proces [...]

Co-expression network models help identify important biochemical pathways, biomarkers, and targets for research, but they typically focus on gene expression. In this work [...]

Dr. Joan Ash joined the Oregon Health and Science University Libraries as Associate Director in 1976. She first became interested in library science as a volunteer at Swa [...]

This thesis focuses on the development of early cancer detection methods for oral and pancreatic cancer through the design of a novel system for liquid biopsy-based bioma [...]