Liquid biopsy provides a minimally-invasive alternative to solid tissue biopsy for assessing tumor-derived molecules such as circulating tumor DNA (ctDNA). Detection and [...]

Many genetic variants are of unknown significance (VUS). Efficient and accurate electronic health record (EHR) phenotyping, having facilitated genome-wide association stu [...]

In behavioral neuroscience, questions of development and function are often pursued using either genetic or imaging approaches. The genetics of behavior has been studied [...]

Genotypes and phenotypes are fundamental to many areas of the life sciences. Biomedical and animal model databases contain a wealth of information about genetics, genomic [...]

Single nucleotide polymorphism genotyping provides a method of genotyping ideally suited to high throughput operations. However, individual variation at SNP loci presents [...]

Bridging the gap between genotype and phenotype is one of the foremost goals of biomedicine, and consequently biomedical informatics. Effective networking between biologi [...]

In recent years, there has been a significant academic drive to determine the cause of the missing heritability problem which is commonly associated with the genetics of [...]

Cognitive deficits are an early feature of Alzheimer’s disease (AD) and vascular dementia (VD). Brain white matter hyperintensities (WMH), identified with MRI, are though [...]