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The gut microbiome is involved in promoting or inhibiting (protecting against or contributing to the development of) many diseases, such as diabetes, inflammatory bowel d [...]
2023-07-21 |
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Immune checkpoint inhibitors have shown success in treating a subset of patients with certain late-stage cancers. However, these treatments fail in many other patients, d [...]
2023-08-18 |
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Despite their devastating impacts on millions of people, most rare and congenital disorders remain poorly understood, leaving the patients with these disorders with no FD [...]
2023-07-20 |
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Acute Myeloid Leukemia (AML) is an aggressive cancer with poor overall survival due to frequent relapse. FMS-like tyrosine kinase (FLT3) is the most commonly mutated gene [...]
2022 |
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Next generation sequencing (NGS) and single-cell sequencing technologies have enabled unparalleled resolution of the cell's molecular machinery; however, gleaning accurat [...]
2021 |
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A major challenge in precision oncology is accurately modeling the molecular machinery that governs cellular sensitivity or resistance to a given drug or drug combination [...]
2020 |
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Abnormal splicing events can promote drug resistance in a variety of cancer types, however, the full extent of genome-wide splicing in therapy-resistant AML is not fully [...]
2020 |
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There has been a growth of interest in the application of quantum computation and quantum simulation to the many intractable computational problems in the biological scie [...]
2020 |
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Rett syndrome is a neurological disease due to loss-of-function mutations in the transcription factor, Methyl CpG binding protein 2 (MECP2). Because overexpression of end [...]
2023-09-13 |
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